HomeScienceWill this new superpower molecule revolutionize science?

Will this new superpower molecule revolutionize science?

master mentalism tricks

When scientists discovered DNA and learned how to control it, not only science but society was revolutionized. Today researchers and the medical industry routinely create artificial DNA structures for many purposes, including diagnosis and treatment of diseases.

Now an international research team reports to have created a powerful supermolecule with the potential to further revolutionize science.

The work is published in Nature Communications. Authors are from University of Southern Denmark (Denmark), Kent State University (USA), Copenhagen University (Denmark), Oxford University (UK) and ATDBio (UK). Lead authors are Chenguang Lou, associate professor, University of Southern Denmark and Hanbin Mao, professor, Kent State University, USA.

Next generation of nanotechnology

The researchers describe their supermolecule as a marriage between DNA and peptides.

DNA is one of the most important biomolecules, and so are peptides; peptide structures are used, among other things, to create artificial proteins and various nanostructures.


“If you combine these two, as we have, you get a very powerful molecular tool, that may lead to the next generation of nanotechnology; it may allow us to make more advanced nanostructures, for example, for detecting diseases,” says corresponding author Chenguang Lou, associate professor at Department of Physics, Chemistry and Pharmacy, University of Southern Denmark.

The cause of Alzheimer’s

According to the researchers, another example is that this marriage of peptides to DNA can be used to create artificial proteins, which will be more stable and thus more reliable to work with than natural proteins, which are vulnerable to heat, UV, chemical reagents, etc.

“Our next step will be to investigate whether it can be used to explain the cause of Alzheimer’s disease in which malfunctional peptides are culprits,” says the other corresponding author, Hanbin Mao, professor at Chemistry and Biochemistry, Kent State University.

The research work reports the mechanical properties of a new structure composed of three-stranded DNA structures and three-stranded peptide structures. It may sound simple, but it is far from.


Left and right in nature

It is rare in Nature that DNA and peptide structures are chemically linked like this new structure is.

In Nature, they often behave like cats and dogs, though some key interactions are essential to any living organisms. One possible reason for this is their so-called chirality — sometimes also described as handedness.

All biological structures, from molecules to the human body, have a fixed chirality; think of our heart, which is always positioned in the left side of our body. DNA is always right-handed and peptides are always left-handed, so trying to combine them is a highly challenging task.

Changing left to right

“Imagine you want to stack your two hands by matching each finger while both palms face the same direction. You will find out it is impossible to do it. You can only do this if you can trick your two hands into having the same chirality,” says Hanbin Mao.

This is what the research team has done; tricked the chirality. They have changed the peptide chirality from left to right, so it fits with the chirality of the DNA and works with it instead of repelling it.

“This is the first study to show that the chirality of DNA and peptide structures can communicate and interact, when their handedness is changed,” says Chenguang Lou.

So why do we have a left and a right hand?

The researchers report to be the first to provide an answer to why the biological world is chiral:

“The answer is energy: the chiral world requires the lowest energy to maintain, therefore it is most stable,” says Hanbin Mao.

In other words: Nature will always seek to spend as little energy as possible.

Read The Full Article Here

trick photography

Popular posts

‘Murder Mystery 2’ Trailer: Sandler and Aniston, Back on the
Eddie Murphy Wants to Make ‘Shrek 5’ or a Donkey
Invincible Season 2 Teaser Trailer Sets Release Date Window
YOLO: Silver Destiny Interview: Michael Cusack, Todor Manojlovic, & Sarah
Watch La Brea Online: Season 2 Episode 8
TNets Push ‘Lazarus Project,’ ‘Miracle Workers’ Premieres
Speaking ‘Truth’ to Power, ‘Real Time’ and ‘Game Theory’ Back
Good Wife Spinoff, Matlock Series Starring Kathy Bates Among CBS
Duval Timothy Shares New Video for “First Rain”
Unknown Mortal Orchestra Detail New Album V, Share Video for
Fatima Al Qadiri Announces New Gumar EP, Shares New Song
Future, Missy Elliott, the Roots, Glorilla, and More to Perform
Hailey Bieber Short Hair: Bieber Spent Weeks Thinking About Cutting
Anne Hathaway Dancing at Valentino Proves That Hathaway Is Thriving
These Rollerball Perfumes Smell Intoxicatingly Good (and Are Carry-On Approved)
I’m a Style Expert, and These 12 New-Season Buys Have
Interview with T.W. Pearce, Author of Forbitten Fae
Book Riot’s Deals of the Day for February 2, 2023
Deliciously Disturbing and Addictive Sequel to ‘River of Ashes’
Books & Looks Podcast: Bad City, The Dark Side of
Microparticles could help prevent vitamin A deficiency: Fortifying foods with
Are Quantum Computers about to Break Online Privacy?
Compound reverses gut inflammation in mice
NASA’s Orion capsule captures gorgeous close-up pictures of the moon
Watch the Trailer for The Guardians of the Galaxy Holiday
The Best USB Flash Drives for Ultra-Portable Storage
Apple Asks Suppliers to Decarbonise, Announces New Clean Energy Investments
Bitcoin Breaks Above $20,000 as Investors Turn to Riskier Assets