Artistic rendering of the CRISPR Cas 7-11S enzyme. Credit: Steve Dixon Last year, researchers at MIT’s McGovern Institute for Brain Research discovered and characterized Cas7-11, the first CRISPR enzyme capable of making precise, guided cuts to strands of RNA without harming cells in the process. Now, working with collaborators at the University of Tokyo, the same team has revealed that Cas7-11 can be shrunk to a more compact version, making it an even more viable option for editing the RNA inside living cells. The new, compact Cas7-11 was described May 27 in the journal Cell along with a detailed structural…
Author: Admin
In the ’90s, Ghost was one of the first places you’d visit when looking for a new dress, as its silky slip dresses were the height of cool. However, the brand gradually became seen as a destination for pastel bridesmaid frocks and occasion-wear only. But Ghost has become cool again over the couple of years thanks to a reboot of its button-front tea dresses and silky midi dresses. And our team, like the many influencers we follow on Instagram, are all in agreement that this is now one of the very best places to snap up a quality, classic dress design in 2022.And it…
The government is coming up with a regulation that will make organisations hit by any cybercrime incidence to disclose it before the government, Minister of State for Electronics and IT Rajeev Chandrasekhar said on Wednesday.While speaking at the launch of the IBM Security Command Centre for Asia Pacific region set up in Bengaluru, Chandrasekhar said about 100 million-odd cyber incidents have been reported by the Indian-CERT (Computer Emergency Response Team) so far and India is reportedly the second-most attacked country as far as cyber crime is concerned.”You will soon hear in the next few days that new regulations going out…
On the Monday (June 13) episode of the long-running TV quiz show Jeopardy!, punk rock icons The Offspring were the subject of one of the questions under the “Rock” category.The list of names of rock and metal artists and musicians who have been featured in some capacity — be it part of a clue or the answer to the clue — continues to grow and the inclusion of so many notable figures in heavy music is starting to feel increasingly commonplace. While this music has been shunned by the mainstream for the last decade at the least, there’s something to say…
Three children with a rare genetic disease needed kidney transplants, and by using a unique transplantation technique, doctors successfully replaced the kids’ kidneys without the need for any immune-suppressing drugs.Typically, after receiving a transplant, organ recipients must take immunosuppressive drugs for the rest of their lives, in order to prevent the immune system from rejecting the organ. This places organ recipients at an increased risk for infections and cancer, and even then, the immunosuppressants don’t eliminate the risk that the body will eventually reject the organ anyway.In order to reduce or eliminate the need for immunosuppression, doctors have tried transplanting…
How Deep Throat and Pleasure ask questions about safety on porn sets 3 && args[2] === 2 && typeof args[3] === ‘boolean’ ) { gdprApplies = args[3]; if (typeof args[2] === ‘function’) { args[2](‘set’, true); } } } else if (args[0] === ‘ping’) { var retr = { gdprApplies: gdprApplies, cmpLoaded: false, cmpStatus: ‘stub’ }; if (typeof args[2] === ‘function’) { args[2](retr); } } else { queue.push(args); } } function postMessageEventHandler(event) { var msgIsString = typeof event.data === ‘string’; var json = {}; try { if (msgIsString) { json = JSON.parse(event.data); } else { json = event.data; } } catch…
What’s the story behind the story? What inspired you to write Hawaiian Paradise Surprise? While watching the athletic, handsome surfers in Molokai, Hawaii one afternoon, I experienced a burst of creativity to write a romance featuring Nash Denning, a legendary surfer, and Jill Cabott, a bestselling author. Jill is reluctant to entertain romance after being widowed in the prime of her life, but as she discovers her self-esteem again, she connects with two men—the dashing Nash and Ben Warner, a recently retired businessman. If you had to pick theme songs for the main characters of Hawaiian Paradise Surprise, what would…
It was evident that the Bellweather Trio would have to unlearn much of the disciplined training they had received at Fort Salem. Motherland: Fort Salem Season 3 Episode 1 proved that Scylla would have to take the lead for the fugitives because the rest are woefully unprepared to live life on the run. Most of them didn’t get the concept of lying low, and, as a result, they were back on the road by the end of the episode. Yup, it’s good that they have both Scylla (ex-Spree, ex-Dodger) and Nicte (ex-Spree, longtime fugitive) on hand to offer their hard-won wisdom.…
Photography by Inez & Vinoodh Introducing Haus Labs by Lady Gaga, a new and improved extension of her individuality. By Natalie Michie Date June 9, 2022 It’s 2:30 p.m. on a Tuesday and Lady Gaga is swatching makeup for me over Zoom. A new clean beauty aficionado, she’s telling me about ingredients like plant squalene and hyalurionic acid, periodically holding up the back of her hand to give me a good look at the pigmented lines on her skin. She then spots the magenta lipstick I had swiped on minutes before our call. “I’ll have to send you this lip…
[Thread] A look at Kraken’s announcement of a culture overhaul, eschewing “stereotypical team diversity measurements”, as the crypto exchange touts hiring plans — Kraken, a U.S.-based crypto exchange, has announced they’ll be continuing to hire, and have announced a culture overhaul that promotes “diversity of thought” over “stereotypical team diversity measurements” and prohibits describing another’s words as “racist” or “x-phobic”. 🧵 Read The Full Article Here
Even Robert Fripp and Toyah Willcox are psyched for Rage Against the Machine’s long-awaited reunion tour. The married musical couple take on “Killing in the Name” for their latest “Sunday Lunch” performance, which comes less than a month from the kickoff of RATM’s first tour in more than a decade. A few days ago, RATM themselves got us pumped up for the tour by posting a new rehearsal clip of the band performing “War Within a Breath.” The tour launches July 9th in East Troy, Wisconsin, with tickets available here. Now, King Crimson guitarist Fripp and his singer wife, Toyah,…
Cycling shoes aren’t known for their cocoon-like comfort, nor are they renowned for their looks, so we were over the moon to find the Giro Regime Cycling Shoes offered style and substance (without sacrificing performance).Slipping into the shoe feels like wearing a second sock, with the sleek Synchwire upper seemingly molding to the shape of our feet instantaneously. We also loved being able to fasten them around our ankles and forefoot in less than a second by twisting the dual Boa L6 dials to our desired tightness – with many of the other best shoes for Peloton (opens in new…
Baby is back.It was first announced by Lionsgate at this year’s CinemaCon back in April, and now the project is moving forward. The untitled Dirty Dancing sequel, which features the original movie’s star, Jennifer Grey, reprising her role as Baby, will open in theaters in time for Valentine’s Day in 2024.According to Deadline, here is what the movie is about: “In part 2, Baby (Grey) takes us back to Kellerman’s Resort for a story of summer, young romance, and dancing.” So not exactly a bold departure from the source material, then.The sequel will be directed by Jonathan Levine, whose previous work includes 50/50, The…
Read The Full Article Here
ABC is the second broadcast network to announce its fall premiere dates, and it’s business as usual. The season gets underway Wednesday, September 21, with the season debuts of The Conners, The Goldbergs, Abbott Elementary, Home Economics, and Big Sky. This will be a big test for Big Sky, which is moving from Thursday. It is getting an injection of star power, courtesy of Jensen Ackles and Reba McEntire as the latest mystery gets underway. Sunday, September 25, marks the series debut of Celebrity Jeopardy, as well as the returns of Celebrity Wheel of Fortune and The Rookie. The Rookie…
As POPSUGAR editors, we independently select and write about stuff we love and think you’ll like too. If you buy a product we have recommended, we may receive affiliate commission, which in turn supports our work. Kim Kardashian and Pete Davidson took their matching hairstyles one step further while out in London on May 29, this time also coordinating in all-black outfits. Kardashian, sporting Balenciaga head to toe, paired the brand’s shrunken political-statement zip-up hoodie with her go-to spandex pantaleggings, finishing the outfit with her fluffy Hourglass bag (that she’s been showing off quite often this spring). Kardashian’s platinum-blond hair…
[Thread] A look at Kraken’s announcement of a culture overhaul, eschewing “stereotypical team diversity measurements”, as the crypto exchange touts hiring plans — Kraken, a U.S.-based crypto exchange, has announced they’ll be continuing to hire, and have announced a culture overhaul that promotes “diversity of thought” over “stereotypical team diversity measurements” and prohibits describing another’s words as “racist” or “x-phobic”. 🧵 Read The Full Article Here
Pink Floyd has joined TikTok, the band announced on Monday (May 30). After just one day on the app, the veteran English psych rockers have have amassed more than 7,500 followers and shared two different videos. The first features a hypnotic spinning pyramid set to “Breathe (In the Air)” to commemorate the pending 50-year anniversary of their seminal album The Dark Side of the Moon, which turns half-a-century old next spring. Posted just hours later, Pink Floyd’s second video is more straightforward in heralding their arrival on the popular social media platform. Text appears on the screen reading “PINK FLOYD…
For Native Americans, kya (the turtle) symbolizes wisdom. For Europeans, bears are an important element of their history. What animals mean the most to you, and why do they hold such significance? Cultures worldwide have empowering relationships with wild animals and knowing those animals promotes a deeper connection to spirituality, geography and pride. For Black people, our connection to nature and the cultural significance of mammals comes from traditions practiced during the slavery era and continues into modern-day pop culture. As we commemorate the nation’s newest federal holiday on June 19, Juneteenth (observed this year on Monday, June 20) provides…
You have to like a movie star who is honest about himself and his career. Tom Hanks will defend his work from criticism, as well he should, but he’ll also admit when something was, in his words, a bunch of “hooey.”Take his trilogy of movies based on Dan Brown’s historical thriller novels about the adventures of a symbologist who solves mysteries surrounding ancient conspiracies. They started with 2006’s The Da Vinci Code, and continued through 2009’s Angels & Demons, and finally 2016’s Inferno. The first movie, which was based on Brown’s biggest best-seller, was a huge blockbuster, grossing well over $750 million worldwide. Each sequel…
An artist’s impression of a fast-expanding supermassive black hole from far away. (Image credit: Shutterstock) (opens in new tab)Astronomers have detected the brightest and fastest-growing black hole to have existed in the last 9 billion years. The enormous cosmic entity is 3 billion times more massive than the sun and swallows up an Earth-size chunk of matter every second.The new supermassive black hole, known as J1144, is around 500 times as Sagittarius A*, the supermassive black hole at the heart of the Milky Way, which was recently photographed for the first time. A ring of superhot plasma around the enormous…
16 Jun 2022 Romance Reads You’ll Love | June 2022 In the mood for a new romance read this week? Check out our favorite sweet romance, paranormal, romantic suspense books, and more from bestselling authors Alexi Venice, Susan Sands, Charmaine Ross, Winter Renshaw, Emma St. Clair, C.M. Steele & more. Enjoy your new romances! Hawaiian Paradise Surprise by Alexi Venice Release Date: May 19, 2022 Award-winning and bestselling author Alexi Venice delivers a powerful, thought-provoking romance in paradise about a young widow struggling to finish her current writing project while being pursued by a carefree surfer and an eccentric businessman.…
For the first time in nearly 13 years, The CW’s Vampire Diaries universe is off the air. With spinoff series Legacies‘ fourth season serving as its last, and its June 16 finale already behind us, there’s no telling when another TVD story will come about. However, during their run, TVD shows became the pinnacle of the supernatural soap genre with steamy romances, intriguing lore, memorable characters — and most importantly, a perfect amount of cheesiness (at least, when it wasn’t trying to be too serious). When it premiered in 2018 soon afterThe Originals finale, Legacies found ways to distinguish itself…
“Maid” actress Margaret Qualley recently got engaged to record producer Jack Antonoff, confirming the news on May 31 by sharing a gallery of Instagram selfies that highlight her engagement ring. The piece of jewelry features a round-cut diamond set on a white-gold split-shank band, and there appear to be two smaller diamonds nestled into where the band divides on each side, providing some additional sparkle. It has an antique charm to it and is a welcome departure from some of the far more elaborate rings we’ve seen on other celebrities this year. Seeing as the vintage aesthetic is a big…
[Thread] A look at Kraken’s announcement of a culture overhaul, eschewing “stereotypical team diversity measurements”, as the crypto exchange touts hiring plans — Kraken, a U.S.-based crypto exchange, has announced they’ll be continuing to hire, and have announced a culture overhaul that promotes “diversity of thought” over “stereotypical team diversity measurements” and prohibits describing another’s words as “racist” or “x-phobic”. 🧵 Read The Full Article Here
Welcome to Dissected, where we disassemble a band’s catalog, a director’s filmography, or some other critical pop-culture collection in the abstract. It’s exact science by way of a few beers. This time, we sort through the best and worst of the franchise born from a simple question: What if dinosaurs lived again? For over three decades now, the Jurassic franchise has dwelled happily at the intersection of horror and action, but when digging into them, what stands out is how the ones which feel the least successful are the ones that feel compelled to treat this as a monster movie…
Twenty seconds of scrubbing with soap is one of the best ways to protect yourself — and the people and things you touch — from disease-causing germs. But how exactly do soapy suds kill pathogenic bacteria and viruses that infect us?Soap’s germ-zapping superpowers are built into its molecular structure: a “head” attached to a long “tail,” according to Dr. Lee Riley, a physician, professor and chair of the Division of Infectious Disease and Vaccinology at the University of California (UC) Berkeley. The head is hydrophilic, or water-loving, while the tail is hydrophobic — water-fearing or water-repelling. That hydrophobic tail has…
There are now 28 movies in the Marvel Cinematic Universe. All 28 have been rated PG-13. That includes the latest film, Thor: Love and Thunder.This PG-13, though, is different from the others. Thor: Love and Thunder is rated PG-13 by the Motion Picture Association of America “for intense sequences of sci-fi violence and action, language, some suggestive material and partial nudity.” It’s the first time a Marvel movie has gotten rated for any nudity, partial or otherwise.The most recent MCU movie, Doctor Strange in the Multiverse of Madness, was rated PG-13 “for intense sequences of violence and action, frightening images and some…
Read The Full Article Here
[Warning: The following contains MAJOR spoilers for the I Love That For You Season 1 finale, “Shop Cancer’s Ass.”] Vanessa Bayer brings her perfectly cringe comedic stylings to Showtime‘s I Love That For You, a series inspired by her own experiences with childhood cancer. Created by Bayer and Jeremy Beiler (Saturday Night Live), the debut season of I Love That For You proved itself to be a singular comedy with a unique brand of humor and drama. Bayer’s Joanna Gold’s dreams come true when the home shopping superfan lands a job at the Special Value Network, where Joanna’s idol, Jackie…