HomeScienceNew studies demonstrate advancements in nanotechnology and their impact across

New studies demonstrate advancements in nanotechnology and their impact across


master mentalism tricks

Recent progress in nanotechnology paves the way for improved drug delivery, clinical diagnosis, and even environmental protection against toxic pollutants. Credit: Journal of Pharmaceutical Analysis

Active nanotech-based research from China has yielded several new advancements with wide-ranging applications. Newly developed nanosensors can be used to detect toxic environmental pollutants, such as chromium; novel medical technologies can be leveraged to allow point-of-care testing for clinical diagnosis and drug analysis; and they can even provide sustained and controlled drug release. Accordingly, these new technologies are expected to usher in an era of improved healthcare at the levels of prevention, diagnosis, and treatment.

Nanotechnology research has found applications in many fields, from medicine and drug research to aeronautics and automobiles. A series of recent studies from Chinese researchers, which were published in the Journal of Pharmaceutical Analysis, have contributed further to nanotechnology research.

The first study, made available online on May 1, 2021 and published in Volume 12 Issue 1 February 2022 of the journal, was published by researchers from Anhui University of Chinese Medicine. These researchers set out to solve the problems caused by environmental contamination with chromium, a carcinogen. They developed nanodots made of carbon using natural polysaccharides from Poria mushrooms, which have no pharmacological activity. These nanodots functioned as an “on-off” fluorescent probe with the ability to detect environmental chromium.

Speaking about the applications, the researchers say, “With their inexpensive source material, these nanodots allow for cost-effective and quick chromium detection, and their efficacy has been proven using actual water samples. They also represent a new avenue for the non-pharmacological application of traditional Chinese medicines and could help prevent serious health problems.”

In another study, made available online on March 31, 2021 and published in Volume 12 Issue 1 February 2022 of the journal, researchers from Chongqing Medical University and Chongqing Normal University found a way to regulate the peroxidase activity of molybdenum-based quantum dots that acted as “nanozymes” (small artificial enzymes). These nanozymes caused a color change in the presence of a particular drug, and the intensity of the color change reflected the concentration of the drug.

The researchers state, “These nanosensors could be used to detect drug concentrations depending on the intensity of the color change. Therefore, they could be used to develop robust pharmaceutical detection platforms to make drug assays and diagnosis easier, improving the standard of healthcare.”

In the final study,  made available online on March 9, 2021 and published in Volume 12 Issue 1 February 2022 of the journal, researchers from Lanzhou University used nanotechnology to develop better drug formulations. Controlled drug release helps in targeting tumors and cancer more effectively, but there are few approaches that allow controlled drug release in a tumor’s intracellular microenvironment. Therefore, researchers developed a mixed drug self-delivery system (DSDS) with a high drug content that contained two forms of the chemotherapy drug doxorubicin. This system provided sustained pH-triggered drug release, which could be adjusted by manipulating the ratio of the two forms of the drug.

Interestingly, laboratory tests showed that the slow-release mixed DSDS nanoparticles were highly effective in killing cancer cells. “Therefore, this platform could serve as a suitable treatment system, providing improved patient outcomes in the future,” the researchers conclude.

Progress in the application of nano- and micro-based drug delivery systems in pulmonary disease More information: Qianqian Huang et al, Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection, Journal of Pharmaceutical Analysis (2021). DOI: 10.1016/j.jpha.2021.04.004

Juan Tan et al, Reversible regulation of enzyme-like activity of molybdenum disulfide quantum dots for colorimetric pharmaceutical analysis, Journal of Pharmaceutical Analysis (2021). DOI: 10.1016/j.jpha.2021.03.010

Jiagen Li et al, Regulation of drug release performance using mixed doxorubicin-doxorubicin dimer nanoparticles as a pH-triggered drug self-delivery system, Journal of Pharmaceutical Analysis (2021). DOI: 10.1016/j.jpha.2021.03.001

Provided by Cactus Communications

Citation: New studies demonstrate advancements in nanotechnology and their impact across multiple areas of human health (2022, April 7) retrieved 6 May 2022 from https://phys.org/news/2022-04-advancements-nanotechnology-impact-multiple-areas.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Read The Full Article Here


trick photography
Advertisingfutmillion

Popular posts

Hollywood Spotlight: Director Jon Frenkel Garcia
The Dutchman Cast: André Holland, Zazie Beetz & More Join
The Creator Reactions: Gareth Edwards’ Latest Is One of 2023’s
Company Paid Critics For Rotten Tomatoes Reviews
‘Fraggle Rock: Back to the Rock’ Season 2 Heading to
FBI Season 6 Episode 6 Review: Unforeseen
The Good Doctor Season 7 Episode 4 Review: Date Night
These Horror Book Series Would Make Great TV Adaptations
Bill McBirnie’s Reflections (For Paul Horn) 
“Be Big” by Stephanie Bettman
“Ride On” by Roots Asylum
Touch the Buffalo’s “Bodhicitta”
9 Boob Tapes That Work For All Busts, Shapes, and
Here’s Why Apple Cider Vinegar Is the Ingredient Your Hair
I Travel a Lot for Work—These Are the Useful Items
The Best Street Style Looks From the Fall 2023 Couture
Latest in Mystery Series Follows P
Children’s Book Phenom Anoosha Syed Launches Latest
Winter 2024 Pick: The Heaven & Earth Grocery Store
Bookshelf: Development Diary
Butterflies could lose spots as climate warms
The FDA recently approved semaglutide (Wegovy) for preventing serious heart
10 years after the deadliest US landslide, climate change is
Researchers pump brakes on ‘blue acceleration’ harming the world ocean
Killing TikTok
Comedy or Tragedy?
BYD Atto 3 Electric SUV With Blade Battery Technology Launched
Bitcoin Falls to $19,000 in Anticipation of Tighter Fed Policy