Inside the leading edge of a crawling cell, intricate networks of rod-like actin filaments extend toward the cell membrane at various angles, lengthening protein by protein. Upon impact, the crisscrossing rods glance off the membrane and bend as the collective force of myriad filaments pushes the cell forward. How flexible these filaments are, and how effectively they recruit essential regulatory proteins to their cause, depends on the properties of the individual actin proteins composing them. Now, a new study in Nature provides high-resolution structures showing how two key biochemical states of actin work jointly with bending forces to determine how…
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While Christmas is not, in actuality, a holiday I specifically celebrate, it is a day of the year that I really enjoy. Even where I live, in the very un-wintery Los Angeles, Christmas does have a unique air about it. The streets empty and all the transplants depart town, leaving L.A. empty and still for this one day out of the year. And this stillness, to me, is the perfect atmosphere for curling up with a stack of books and some tea, and having a cozy day all to myself. This year, let’s make Christmas — or any of the…
[Warning: The below contains MAJOR spoilers for The Midnight Club Season 1.] It’s always a sad day when a show with lingering mysteries is canceled, but such is the case with The Midnight Club at Netflix. Inspired by the works of Christopher Pike and hailing from horror auteur Mike Flanagan, The Midnight Club‘s chances for survival shrunk after it was revealed Flanagan and collaborator Trevor Macy had signed a new multi-year deal with Amazon Studios, a direct competitor with Prime Video. Just hours after the deal was announced, The Midnight Club was axed by Netflix. Unlike Flanagan’s past works like…
Microplastic samples collected from the North Atlantic during the eXXpedition Round the World voyage. Credit: Sophie Dingwall The waters of the North Atlantic gyre contain significantly greater quantities of plastic—composed of polymers arising from packaging, rope, and paint particles—than other areas of the open ocean, according to new research. One of the planet’s five great oceanic gyres, manmade marine debris becomes trapped in a circular ocean current that stretches from the east coasts of North America to the west coasts of Europe and Africa. A new study, published in Marine Pollution Bulletin, has found it contains higher levels of polyethylene,…
Photography courtesy of Imaxtree Calling all snow bunnies! By Lauren Knowles Date December 2, 2022 Is blush the star of TikTok’s 2022 beauty trends? Summer’s “sunburn blush” turned winter’s frostbitten “I’m cold” makeup look tells us it just may be. The beauty embodiment of Jack Frost nipping at your nose, this viral makeup trend suggests having just escaped frigid temperatures with its telltale rosy cheeks. With several first snow sightings across Canada this week, we could naturally achieve this look after only a few moments spent outside — but we can also create the illusion of having done so with…
Elon Musk has said that he intends to replace Parag Agrawal as CEO of the social media platform and also intends to reverse the permanent ban on users, according to a Bloomberg report. Agrawal was fired along with other major executives upon completion of the takeover, Bloomberg reported on Friday, citing a person familiar with the matter. The Tesla and SpaceX CEO is expected to remain CEO of Twitter in the interim period but may eventually cede the role in the longer term, the report said.According to multiple US media reports, Twitter’s Chief Financial Officer Ned Segal and Vijaya Gadde…
Andy Rourke went on to play in a bunch of other bands after The Smiths broke up in 1987, his most recent of which being Blitz Vega with former Happy Mondays guitarist Kav Blaggers. The duo have a single out now called “Strong Forever,” which features licks from fellow ex-Smith Johnny Marr, marking the first new music they’ve recorded together in 35 years. “Strong Forever” is set to appear on Blitz Vega’s upcoming album, and as Rourke told Rolling Stone, it was originally recorded with then-Kasabian frontman Tom Meighan for a UN/UK football anti-discrimination/anti-bullying campaign. That plan fell through when Meighan pleaded guilty…
Simon Pegg was one of the more surprising stars to show up in The Boys, yet he did not come back in later seasons. However, that is about to change with upcoming fourth season of the superhero show. According to Deadline, the Shaun of the Dead star has signed on to return as Hughie’s father Mr. Campbell in the upcoming fourth season of The Boys, which is currently in production. He will be joined by three new cast members Rosemarie DeWitt (The Staircase), Rob Benedict (Supernatural), and Elliot Knight (Call of Duty: Modern Warfare II), with DeWitt tapped for the role as Hughie’s mom. Pegg has briefly spoken not…
Westbound by K. Patrick Conner What’s it About? Retired newspaper editor Elliott Madison long ago worked on a book about his great-grandparents. When a stranger reaches out about a connection between distant relatives, he is pulled into an investigation about his family history. History fans will fall in love with this simple, yet elegantly told story of human connections across the centuries. A genealogy project documenting the life of his great-grandparent’s westward experiences during the 19th century holds unexpected surprises for retired newspaper editor Elliott Madison in K. Patrick Conner’s charming novel, Westbound (Nacl Press). History Revealed Through Letters and…
Erin and Anthony are constantly crossing each other’s boundaries. Erin has pissed Anthony off by running background checks on people he’s spending time with, and Anthony is never shy about his opinion of Erin’s relationship with Jack. On Blue Bloods Season 13 Episode 8, Anthony irritated Erin by taking surveillance photos of Jack, only for her to realize he was right to be concerned. I thought Erin had officially declared her candidacy long ago, but Anthony was worried about what would happen when she officially filed the paperwork. Is that coming? Because otherwise, this storyline — which has been primarily…
This combo of images shows from the top, an 11th century Romanesque church partially exposed in a reservoir in Vilanova de Sau, Catalonia, Spain, Monday, June 20, 2022, and the same spot on Friday, Nov. 18. 2022. Credit: AP Photo/Emilio Morenatti Barcelona and large swathes of Spain’s northeast are going under water restrictions as a months-long drought that has devastated crops starts to put the pinch on human activities in the Mediterranean country. The measures will affect 6.7 million people, 80% of the population in the Catalonia region, Patrícia Plaja, spokeswoman for the Catalan administration, said Tuesday. Plaja said, for…
It’s been quite the fashionable week in the nation’s capital. On Dec. 1, President Biden’s first state dinner — in which he and First Lady Jill Biden played host to President Emmanuel Macron of France and his wife, Brigitte Macron — brought out a slew of stylish celebrities like Jennifer Garner, John Legend, and Julia Louis-Dreyfus, in addition to fashion tastemakers like Vogue editor-in-chief Anna Wintour and designers Christian Louboutin and Gabriela Hearst. Then, on Dec. 4, the 45th Kennedy Center Honors took place. The annual event pays tribute to notable figures in the performing arts for their contributions to…
Buying a smartphone on a medium-sized budget can be a confusing task, with so many smartphone models available across popular manufacturers such as Samsung, Oppo, Xiaomi, and OnePlus. These handsets are typically equipped with one or two features typically found on more expensive flagship phones, such as faster charging, high-end chipsets, or camera sensors. While it might be argued that you get more value for your money when purchasing a smartphone in this price segment, you might also have to make certain trade-offs.On this week’s episode of Orbital, the Gadgets 360 podcast, host Akhil Arora talks to Reviewer Pranav Hegde…
Actress and singer/songwriter Rita Wilson and Grammy-nominated Latin pop star Sebastián Yatra have teamed up to record the new track “Til You’re Home” for the upcoming film A Man Called Otto starring Wilson’s husband Tom Hanks. Explore See latest videos, charts and news See latest videos, charts and news “I am extremely honored by Rita Wilson’s invitation to join her on ‘Til You’re Home’ for the A Man Called Otto soundtrack,” Yatra said in a statement. “The story behind the film is heartwarming and moving and I was inspired to convey that emotion in this song. Overall, this project has…
It’s been four years since the last Transformers movie, the surprisingly enjoyable prequel/spinoff Bumblebee. The franchise’s latest effort is a more typical sequel, with the full cast of the franchise back — along with new characters inspired by the 1990s Beast Wars series of cartoons, games, comics, and toys.Dubbed Transformers: Rise of the Beasts, it features mainstays like Optimus Prime (once again voiced by Peter Cullen) and Bumblebee, along with new characters like Optimus Primal (voiced by Ron Perlman), and a bunch of other “Maximals” and “Terrorcons.” The new human lead is Anthony Ramos, from Hamilton and In the Heights.Instead of Michael Bay, Rise of the Beasts was directed by Steven…
Colombian environmental engineer Germán Viasus Tibamoso, owner of Tierra Viva, holds a Hercules beetle in Tunja, Colombia, Tuesday, Nov. 15, 2022. The company transforms solid, organic waste, with the help of beetle larvae’s digestive microorganisms, that transform the waste into a compost rich in nitrogen and phosphorous. Once adults, the beetles are sent to scientific labs and others to Japan where they are popular as pets. Credit: AP Photo/Fernando Vergara Three yellow-and-black beetles clung to the shirt of Germán Viasus Tibamoso, a Colombian environmental engineer who uses beetle larvae to transform food waste into fertilizers. As he encouraged them to…
This content contains affiliate links. When you buy through these links, we may earn an affiliate commission. I’ve always liked stories that work out okay. Once, when I was 15 or so, I threw a book across the room because the main character stepped aside so her best friend could marry the man she loved, because her friend loved him, too. (That book was, it turned out, a Jane Austen fan fiction retelling, so the pairing was predetermined. But that’s beside the point.) I loved the main character of this book and was furious that she ended up unhappy. I…
Things are finally starting to look up. A difficult rescue puts everyone at their anxiety threshold on Fire Country Season 1 Episode 8. This rescue also triggers some bad memories from Vince’s past when he lost his daughter. After a night of gambling, Manny comes to work sleep deprived and erratic. This puts him and Vince in a direct collision as each of them is not their true self. The episode was directed by Fire Country’s own Kevin Alejandro, who plays Manny. It is a common consensus that he did an exemplary job, and we can’t wait for him to direct…
America was unprepared for the magnitude of the pandemic, which overwhelmed many counties and filled some hospitals to capacity. A new paper in PNAS suggests there may have been a mathematical method, of sorts, to the madness of those early COVID days. The study tests a model that closely matches the patterns of case counts and deaths reported, county by county, across the United States between April 2020 and June 2021. The model suggests that unprecedented COVID spikes could, even now, overwhelm local jurisdictions. “Our best estimate, based on the data, is that the numbers of cases and deaths per…
I don’t know about you, but I love the start of a new season, particularly the start of autumn/winter. As the leaves turn to fiery orange, and we swap our summer footwear for winter boots, I can’t help but get swept up in that back-to-school feeling, pulling out my trusted knitwear and adding some new A/W trends to my wardrobe. Same for you? If so, it’s only natural that we’re also keen to update our hair as the seasons shift. While in summer, we might opt for lighter, golden hair colour such as balayage, in autumn and winter, it can be fun to embrace those warmer auburn and brunette shades. Nothing gives…
iPhone 14 series was unveiled during the company’s ‘Far Out’ event in September but rumours of next year’s iPhone models, speculated to be the iPhone 15 series, have already started surfacing online. A reputed market analyst has now suggested that the high-end models in Apple’s 2023 iPhone family will debut with solid-state buttons instead of physical volume and power buttons, similar to the home buttons on iPhone 7, iPhone 8 and iPhone SE units. Kuo forecasts that iPhone 15 smartphones would come equipped with three Taptic Engine vibration motors to simulate the feeling of a click. The analyst states that…
Dolly Parton has always been a woman of her word, and she’s holding true to the statement she made back in May. She’s making a rock album. But it’s who she’s got in mind that makes it even more thrilling – Parton wants to get Led Zeppelin’s Robert Plant and Jimmy Page to reunite for a new take on “Stairway to Heaven.”The country star, who originally pushed back on her Rock & Roll Hall of Fame nomination earlier this year, feeling she was unworthy of the title, vowed she’d make a rock record to mark the occasion if she was inducted.…
Every ten years since 1952, the British film magazine Sight & Sound has polled an international roster of critics and directors, in an attempt to answer a thorny question: What is the greatest film of all time?When Sight & Sound did their poll for the first time in 1952, the top choice was Vittorio de Sica’s Bicycle Thieves. Ten years later, the critics top pick was Orson Welles’ Citizen Kane, and for the next 40 years, Kane remained at the top of the Sight & Sound list. Then, in 2012, it was finally dethroned for the first time in half a century by Alfred Hitchcock’s Vertigo.It is 2022, and so, for the eighth…
07 Dec 2022 Discover Inspiring True Stories With These Biographies & Memoirs! Looking for a new biography or memoir book to get invested in this December? Then look no further! Check out our picks for this week’s must-read biography and memoir books. Happy Reading! A Nice Place Full of Good People by Andrew Rivas Release Date: December 6, 2022 A Nice Place Full of Good People is the story about the seventeen days I spent being illegally held in a psych ward after a suicide attempt, what drove me there, and the friends I made along the way. I hope…
[Warning: The below contains MAJOR spoilers for Wednesday Season 1, Episodes 1-8.] Netflix‘s Wednesday may have followed the titular character’s journey to uncovering a mystery across Season 1, but there are still plenty of unanswered questions, especially when it comes to the Addams Family daughter, Wednesday (Jenna Ortega). Thankfully, a second season seems likelier than ever considering the show broke the record for most hours viewed in a week for an English-language series on Netflix. The show unseated Stranger Things with 341.2 million hours viewed in a single week following its debut. Wednesday hails from showrunners Al Gough and Miles…
From affectionate foxes to ruby-eyed frogs and flamboyant flamingos, the shortlist of photographs selected for the Wildlife Photographer of the Year People’s Choice Award display the natural world in all of its awesomeness. Run by the Natural History Museum, London, the People’s Choice Award is open to voters worldwide, who can choose their favorite image at the contest website (opens in new tab) until Feb. 2, 2023. The winner will be showcased at the museum until the photography exhibit closes in July 2023. Highway hyenaA hyena outside of Harar, Ethiopia. (Image credit: Sam Rowley/Wildlife Photographer of the Year )A spotted hyena…
Gisele Bündchen gave a rare hint about her headspace amid media reports that she has hired a divorce lawyer and may be splitting from her husband of 13 years Tom Brady. Bündchen left a prayer emoji comment and liked a post from life coach Jay Shetty detailing how relationships with inconsistent partners do not work. “You can’t be in a committed relationship with someone who is inconsistent with you. Read that again,” the post read. In caption, Shetty added, “Love is a daily effort. Some days it may come easier than others and that’s OK, but what should always stay…
Rabenn remembers the atmosphere of that war room as more dead silence and sweaty, anxious tension than eagerness or anticipation. He knew the possibility of achieving a Ross Ulbricht–style arrest and seizing Cazes’ laptop in a live, logged-in state—not to mention his phone—was a long shot at best. Even after all their international meetings and planning calls over the past months, and in spite of his usual hard-driving enthusiasm, Rabenn found himself quietly expecting their plan to fail.Across the table, Sanchez was logged in to Roosh V. She checked Rawmeo’s profile and confirmed to the group that he was online…
Soundwalk Collective with Patti Smith have announced a deluxe box set reissuing three of their albums: The Peyote Dance, Mummer Love, and Peradam. The collection also includes a seven-track remix record called The Perfect Vision: Reworkings. The remix album will include new interpretations by Brian Eno, Jim Jarmusch, Laraaji, Kaitlyn Aurelia Smith, and more. The deluxe release arrives November 25 via Bella Union. Find the album art and tracklist below. Also below, hear Brian Eno’s remix of “Peradam.”The group’s three albums were inspired by the writings of Antonin Artaud, Arthur Rimbaud, and René Daumal. The Peyote Dance was recorded in…
Every ten years, the British film magazine Sight & Sound polls hundreds of film critics and directors in order to create near-definitive lists of the best movies ever made. In 2012, critics named Alfred Hitchcock’s Vertigo as the finest motion picture of all time. Directors chose Yasujiro Ozu’s Tokyo Story as their top pick.The 2022 list is officially here — and the winners are Jeanne Dielman, 23, quai du Commerce, 1080 Bruxelles for the critics and 2001: A Space Odyssey for the directors. This time, the magazine (which is affiliated with the venerated British Film Institute) arrived at their answers by polling 1639 “film critics, programmers, curators, archivists and academics”…