Author: Admin

Think about how frustrating it is to try to fit a gift into a box that is too small. Sometimes you just need a bigger box. Building a bigger box Nanocages are tiny artificial containers that can be used to deliver therapeutics to a target destination in the body. But some drug molecules are like gifts that are too big for a standard-sized nanocage ‘box’. Now, in an article published today in Nature Synthesis, researchers from the University of Cambridge describe how they have built a super-sized nanocage that could be used to deliver larger drug cargoes. They have built…

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This content contains affiliate links. When you buy through these links, we may earn an affiliate commission. If you want a peek into the workroom, the real T on the untucked lounge, and perspectives on what’s next in drag, check out these books by RuPaul’s Drag Race contestants and winners. These drag queens bring humor, heart, and plenty of originality from the main stage to the book page. Some of them even include photos, life advice, and recipes. And after that, we’ve got some bonus recommendations from RuPaul and other icons in the world of drag. Put on your most…

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Reese Witherspoon is back on the red carpet. On April 13, the actor and producer stepped out for the premiere of “The Last Thing He Told Me,” marking her first public appearance since announcing her split from from ex-husband Jim Toth. Perhaps signaling a new chapter in her life — and subsequently, a new style era — she wore an unexpectedly edgy black leather dress. Though seemingly a simple midi dress from a distance, upon closer inspection, the one-shouldered silhouette featured a sheer floral overlay, tiny cutouts across the bust, a and subtle side slit. Working with stylist Petra Flannery,…

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The bus was stuck. San Francisco’s eastbound 54 Felton line was heading up a narrow residential street when a white SUV coming the other way stopped in the middle of the road. It was a rainy Sunday evening last month, and the bus driver leaned up to the windshield and peered through the haze at the SUV’s pulsing hazard lights before slumping back and exclaiming in surprise, “What the hell? No driver of the car?!”The 54, brought to a halt by an autonomous vehicle belonging to Alphabet’s Waymo, isn’t the only bus that’s run into trouble with San Francisco’s growing…

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The path taken by Cyclone Freddy across the Indian OceanWorld Meteorological Organization The World Meteorological Organization (WMO) is considering whether tropical cyclone Freddy should be named the longest-lasting tropical cyclone on record as it clocks up its 32nd day. “Freddy is pretty unusual,” says Liz Ritchie-Tyo at Monash University in Melbourne, Australia. Most tropical cyclones, which are low-pressure systems that form over warm tropical waters, only last for about six or seven days, she says. Freddy originated off the north-west coast of Australia on 6 February before travelling more than 7000 kilometres across the Indian Ocean to south-east Africa.Advertisement The…

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[Warning: The below contains MAJOR spoilers for Ted Lasso Season 3, Episode 4, “Big Week.”] Since Ted Lasso debuted in 2020, Jamie Tartt (Phil Dunster) has been one of the comedy’s most compelling characters, and Season 3 is proving the point as the cocky soccer player channels his emotions into pumping up his fellow teammates. But a recent turn of events is shifting Jamie’s focus from the team itself to his career as a footballer against new star player Zava (Maximilian Osinski). Eager to surpass the God-like figure, he decides to lean on former foe-turned-ally Roy Kent (Brett Goldstein) for…

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The elusive artist Jai Paul came out of hiding this weekend to give his first-ever live performance — at Coachella, no less. His setlist included songs like “Higher Res,” “He,” “Crush, “BTSTU,” “Jasmine,” “Str8 Outta Mumbai, “Do You Love Her Now,” and “All Night,” along with a brand new track called “So Long.” He was joined by a full live band featuring his brother A.K. Paul (guitar), Fabiana Palladino (keyboards and backing vocals), Rocco Palladino (bass), and Isaac Kizito (drums). Paul thanked fans on Reddit ahead of his historic Coachella performance. “Just wanted to acknowledge the real heads over here…

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John Wick: Chapter 4 is by far the longest movie in the series. It clocks in at 169 minutes, almost three hours full of wild action scenes. Compare that with the first John Wick, which ran just 101 minutes. That’s like a cup of coffee in comparison.As long as John Wick: Chapter 4 is now, it was almost a lot longer. Director Chad Stahelski told Indiewire that the first rough cut for the movie ran roughly four hours, about an hour longer than the version coming to theaters.“To be really honest with you, zero was planned out,” Stahelski explained. “Our first cut was three hours and 45…

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The Last Remains by Elly Griffiths What’s it About? In the anticipated finale to the Ruth Galloway series, Dr. Galloway and DCI Nelson return with their team to solve a 20-year-old cold case to absolve their friend from suspicion. The Last Remains (Mariner Books) will rightfully jump to the top of many mystery lovers’ TBRN (to be read now!!) piles. It is purportedly the 16th and final book in Elly Griffith’s exciting and addictive series about Ruth Galloway, tenured college professor, forensic archeologist and crime solver who routinely aids the Norfolk police in active murder investigations and cold cases. Archaeological…

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River had his genome sequenced as part of the trial, which revealed he has a genetic condition called Gaucher disease. He was then started on an experimental treatment and is now a “typical 2-year-old”Cody Bailey Critically ill babies in Australia have had their lives saved after their genomes were rapidly sequenced as part of a first-of-its-kind trial. Some babies are born extremely sick: for example, they may have seizures or be unable to breathe on their own. It has traditionally been difficult to determine what causes their symptoms. In many cases, children … Read The Full Article Here

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Fashion week in New York is a feast for the senses. All of the senses, really, but specifically, I’m talking about my shoeaholic senses. Each season, I go undercover (mentally) to roam the streets and shows of fashion week to report back to you, dear reader, all the trends you need to prepare for in the season ahead. Looking for spring 2023 fashion trends in the meantime? We’ve got you covered there, too. But here, find all you need to know about what fall 2023 shoe trends will look like, plus shoppable options so you don’t even have to do…

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Stephen Hill is happy to be soaring in the skies above Oahu again. That’s a bit of an exaggeration as Hill’s character, Theodore Calvin, is a chopper pilot on the NBC drama Magnum P.I. But recently, he found himself up in the air as CBS canceled the series after four seasons, only to have NBC scoop it up about six weeks later. In an exclusive interview, the cordial Hill said that he never doubted that the tales of T.C. and the rest of the Magnum gang would continue. “There was something in me that felt so unfinished with this project…

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Biden Administration officials are discussing whether the United States should subject some of Elon Musk’s ventures to national review including the deal for Twitter Inc and SpaceX’s Starlink satellite network, Bloomberg News reported on Thursday, citing people familiar with the matter.The SpaceX chief in recent times has taken to Twitter to announce proposals to end Russia’s war in Ukraine, and also said SpaceX cannot indefinitely fund its Starlink internet service in Ukraine. He later backed down and said he would continue to bear the costs of the service.The discussions to review Musk’s ventures are at an early stage, sources told…

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BLACKPINK captivated the 2023 Coachella crowd Saturday, becoming the first Korean act to perform at the California festival. In true BLACKPINK fashion, the performance was a sight to behold. With special solo breakouts, awe-inspiring group numbers, and a healthy amount of fireworks, BLACKPINK gave fans everything they were hoping for. For starters, the two acts leading up to BLACKPINK set the tone perfectly — Charli XCX brought heaps of energy and some outstanding choreography, and Rosalía rode scooters around the stage while treating fans to some excellent songs off Motomami. And though BLACKPINK’s set ended up being delayed a bit…

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One Fine Morning review – Bittersweet, throbbing realism 3 && args[2] === 2 && typeof args[3] === ‘boolean’ ) { gdprApplies = args[3]; if (typeof args[2] === ‘function’) { args[2](‘set’, true); } } } else if (args[0] === ‘ping’) { var retr = { gdprApplies: gdprApplies, cmpLoaded: false, cmpStatus: ‘stub’ }; if (typeof args[2] === ‘function’) { args[2](retr); } } else { if(args[0] === ‘init’ && typeof args[3] === ‘object’) { args[3] = { …args[3], tag_version: ‘V2’ }; } queue.push(args); } } function postMessageEventHandler(event) { var msgIsString = typeof event.data === ‘string’; var json = {}; try { if (msgIsString)…

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When you walk through a forest, you are surrounded by carbon. Every branch and every leaf, every inch of trunk and every tendril of unseen root contains carbon pulled from the atmosphere through photosynthesis. And as long as it stays stored away inside that forest, it’s not contributing to the rising concentrations of carbon dioxide that cause climate change. So it’s only natural that we might want to use forests’ carbon-storage superpower as a potential climate solution in addition to reducing human greenhouse gas emissions. But climate change itself might compromise how permanently forests are able to store carbon and…

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What started for the iconic magazine as a celebration of the world’s most influential people affecting major global challenges, from climate to public health to democracy to equality, has expanded to something even bigger. The Time100 list now represents innovators, titans, leaders, artists and trendsetters. The literary world is represented once again this year on the newly revealed 2023 TIME100 list of the most influential people in the world.  TIME has been running its 100 Most Influential People list for 20 years. Each year, they select 100 individuals who are setting an example and transforming the world with their ideas,…

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Prepare to be in your bag this fall. No, not in an emotional way—in the literal sense. Fall 2023 bag trends are shaping up to be total dopamine dressing, and I’m here for it. Based on New York Fashion Week’s runways and street style, times are a-changing when it comes to what’s hot and what’s not in purses and bags. Commuters, prepare to swap your assortment of reusable bags for one carry-all tote (it’s about damn time). To all you DIY-ers and eclectic fashionistas who have been dreaming of making a hair dryer into a baguette bag, the time is…

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Credit: CC0 Public Domain New research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark, (April 15-18) has identified several gold-based compounds with the potential to treat multidrug-resistant “superbugs.” With all 19 compounds tested effective against at least one hard-to-treat bacterium and some effective against several, the Spanish researchers say that the gold-based drugs hold great potential as new antibiotics. Drug-resistant infections kill an estimated 700,000 people a year globally and, with the figure projected to rise to 10 million by 2050 if no action is taken, the World Health Organization (WHO)…

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Isobel McMurray is a strong matriarch who never likes to break down. She can do it all and refuses to let anyone tell her any differently. It is Isobel’s birthday on Ride Season 1 Episode 4, but Isobel refuses to leave the barn because her favorite horse is about to give birth. That was just the beginning of the drama that occurs on McMurray Ranch. TV Fanatic scored an exclusive sneak peek at Sunday’s episode, and we’re thrilled to share it with you. Besides Isobel showing some vulnerability, the hour also showed some character insights into Gus, his family history,…

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Resident Evil 4 remake just received a gameplay trailer, ahead of its launch in March 2023. At Capcom’s Resident Evil Showcase, held early Friday, fans were treated to six-minute-long footage for the hotly-anticipated reimagining of secret agent Leon Kennedy’s tale, as he journeys onto a plague-ridden European village. The publisher also confirmed a playable demo for its upcoming Resident Evil Village: Gold Edition, allowing players to test out the third-person mode. The full version launches October 28, across PC, PS4, PS5, Xbox One, and Xbox Series S/X.Resident Evil 4 remake gameplay trailerAs Capcom’s hightest-rated game, it was only a matter…

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Trevor Powers has shared another new Youth Lagoon song, “Prizefighter.” It comes with a video directed by Tyler T. Williams. He’s also announced an extensive North American tour, his first under the Youth Lagoon banner in eight years. It starts in mid-July and continues through mid-October. Check out “Prizefighter” and see the full tour itinerary below.In February, Trevor Powers released the new song “Idaho Alien,” and announced a new record, Heaven Is a Junkyard, which is out June 9. It arrives nearly eight years after the third Youth Lagoon album, 2015’s Savage Hills Ballroom. Between Youth Lagoon projects, Powers released…

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Smash was an NBC drama that ran in the early 2000s. Many people think it ended a bit too early, but luckily, it’ getting its own Broadway play. The show told the story of a group of friends trying to make a living creating and producing Broadway plays. Of course, it’s an extremely demanding field. Sacrifices must be made to have a successful career there. The series largely follows a successful play based on the life of Marilyn Monroe, titled Bombshell.The actual Broadway production which is just now reaching fruition has been in the works since roughly 2015. Luckily, Steven Spielberg…

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Cat-astrophic by Sue Dugan How much does Nick have in common with Cat, his strange new classmate? A surprising amount, as it turns out. They’re both juniors at Laketon High School, they’re in the same history class and they both know each other from a past life. In her Young Adult novel Cat-strophic (Wild Rose Press), Sue Dugan interweaves a story of two timelines and how the events of the past continue to reverberate today — sometimes in unexpected ways. Protagonist Nick DuPont must balance his modern high school life with flashbacks from his time in WWII-era France with his star-crossed lover, Chaton. In…

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Our brains are made of billions of neurons, which are connected forming complex networks. They communicate between themselves by sending electrical signals, known as action potentials, and chemical signals, known as neurotransmitters, in a process called synaptic transmission. Chemical neurotransmitters are released from one neuron, diffuse to the others and arrive at the targeted cells, generating a signal which excites, inhibits or modulates the cellular activity. The timing and strength of these signals are crucial for the brain to process and interpret sensory information, make decisions, and generate behavior. Controlling the connections between the neurons would allow us to understand…

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If you know me, you understand how deep my affinity for comfy clothes that masquerade as dressy clothes runs. Whether it’s a linen shirt and shorts set that feels like pajamas or secretly stretchy trousers, it needs to feel good. I’ve been looking for tops that feel like T-shirts but look like something you could go out in, and I spotted the perfect hybrid with this Old Navy Fitted Puff-Sleeve Paneled Rib-Knit T-Shirt ($18, originally $30). What I Love About Old Navy’s Fitted Puff-Sleeve Paneled Rib-Knit T-Shirt This cotton top has just a bit of spandex, so it hugs my…

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Tyler Jacob Moore made his Hallmark debut on Rise playing Gus Book, an investor interested in helping McMurray ranch. Most of the McMurrays don’t trust him, especially Cash. How pure are Gus’s motives? TV Fanatic chatted with Tyler about Gus’s reasons for investing in the ranch, the romance with Missy, and Gus’s family history. Check it out. Hi Tyler. You recently made your Hallmark debut on Ride. What is your favorite part of the series so far? My favorite part that has aired so far would have to be the dynamic between myself and the family members who aren’t huge…

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This revelation offers insight into why we age and what critical cellular machinery we must keep running to combat age-related diseases, according to Maria Carolina Florian, a stem cell biologist at the Catalan Institution for Research and Advanced Studies who was not involved in the work. To Florian, it suggests the possibility of creating drugs that can maintain this control for stem cells. It looks particularly important, she says, “because of this possibility to be targeted—to be able to reverse aging.”Signer’s lab studied blood stem cells taken from mouse bone marrow. Doctoral researcher Bernadette Chua first extracted marrow from young…

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Husker Dü have announced the release of Tonite Longhorn, a collection of previously unreleased live material. The trio recorded it across four shows at the Longhorn in Minneapolis, Minnesota, between 1979 and 1980. A 2xLP vinyl version arrives on Record Store Day (Saturday, April 22), and the material hits digital platforms on August 25. Check out a 1979 recording of “Do You Remember?” and see the set’s full tracklist below.Thurston Moore wrote the liner notes for Tonite Longhorn. ANd Hüsker Dü’s Bob Mould shared a statement about the latest project:Most artists begin their careers by looking to their heroes for…

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[] Is Léa Seydoux Mia Hansen-Løve’s greatest on-screen muse? 3 && args[2] === 2 && typeof args[3] === ‘boolean’ ) { gdprApplies = args[3]; if (typeof args[2] === ‘function’) { args[2](‘set’, true); } } } else if (args[0] === ‘ping’) { var retr = { gdprApplies: gdprApplies, cmpLoaded: false, cmpStatus: ‘stub’ }; if (typeof args[2] === ‘function’) { args[2](retr); } } else { if(args[0] === ‘init’ && typeof args[3] === ‘object’) { args[3] = { …args[3], tag_version: ‘V2’ }; } queue.push(args); } } function postMessageEventHandler(event) { var msgIsString = typeof event.data === ‘string’; var json = {}; try { if…

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