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    Home»Television»The Grey’s Anatomy Death That Affected Creator Shonda Rhimes The Most
    Television

    The Grey’s Anatomy Death That Affected Creator Shonda Rhimes The Most

    By AdminDecember 16, 2025
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    The Grey’s Anatomy Death That Affected Creator Shonda Rhimes The Most







    Callie (Sara Ramirez) with her arm around George (T.R. Knight) on Grey's Anatomy
    ABC

    “Grey’s Anatomy” has had its fair share of heartbreaking deaths, but one of the casualties hit so hard that it even upset series creator Shonda Rhimes. 

    And no, we aren’t talking about the controversial death of Patrick Dempsey’s Dr. Derek Shepherd in Season 11 of the ABC medical drama. Though that one was especially tough for fans, considering Derek and Meredith Grey (Ellen Pompeo) were the drama’s central couple, Rhimes remains haunted by a different demise. 

    During an appearance on the “Call Her Daddy” podcast, Rhimes revealed that it was the passing of George O’Malley (T.R. Knight) in the Season 6 premiere that hurt her the most. While fans were upset at losing one of the best “Grey’s Anatomy” characters, Rhimes was sad about having to say goodbye to a colleague behind the scenes. 

    “George was really… That character is so beloved,” Rhimes said. “T.R. is such a lovely guy. That was such a hard thing to do. T.R. is so amazing. That was such a hard thing to do… He was wonderful.”

    Rhimes also praised Knight’s professionalism at the time, noting that he was fully committed to making George’s death impactful — so much so that he even lay on a medical table for a scene in which a body double could have sufficed. 

    For those who may need a refresher, let’s revisit all the particulars about George O’Malley and how he reached the pearly gates on “Grey’s Anatomy.”

    How did George O’Malley die on Grey’s Anatomy?


    George (T.R. Knight) looking at someone on "Grey's Anatomy"
    ABC

    George O’Malley was portrayed as a flawed human being on “Grey’s Anatomy,” as evidenced by his extramarital affair with Izzie Stevens (Katherine Heigl). At the same time, he was compassionate, likable, and great around patients, making him a fan-favorite. 

    The beloved character ultimately received a send-off fir for a hero: He died after being hit by a bus while saving someone else, which spoke volumes about the type of person he was.

    But George’s death occurred amid a particularly tragic set of circumstances. At the time of his passing, he was set to embark on a new career as a medical surgeon; his life ended just as an exciting new chapter was set to begin. Plus, many viewers were especially heartbroken when George was killed off, as it meant there was no avenue for the character to return after T.R. Knight decided to part ways with the medical drama.

    Unfortunately, George’s death wasn’t the only major one to occur on “Grey’s Anatomy,” nor will it be the last. The medical drama is still going strong, and that means our favorite characters could find themselves in harm’s way at any given moment.



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