Can weight-loss drugs ditch the needles?Aleksandr Zubkov/Getty Images A daily pill appears to lower blood sugar in people with type 2 diabetes as effectively as injectable drugs like Ozempic and Mounjaro. The medication, called orforglipron, also led to substantial weight loss in clinical trials, meaning it could become a convenient alternative to popular weight-loss drugs. Drugs mimicking the hormone GLP-1, which regulates appetite and blood sugar, have exploded in popularity. Known as GLP-1 agonists, these medications can treat obesity, type 2 diabetes and heart disease. One downside is that nearly… View Original Source Here
Author: Admin
A Price Is Right contestant fell on the ground on set after winning a lot of money on the Showcase wheel. The contestant first won $1,000 after spinning 100, and then got a second chance to win more money. The episode was a special “All Cash Friday” where all of the prizes were money. Sabrina Miller was one of the first contestants called to Bidder’s Row on Friday, April 18. She bid $2,000 on a trip for two to Santa Fe, New Mexico. That was the highest price and since the retail price was $2,896, she won. For her game,…
Spectacles of suffering and fascism in cinema About Little White Lies Little White Lies was established in 2005 as a bi-monthly print magazine committed to championing great movies and the talented people who make them. Combining cutting-edge design, illustration and journalism, we’ve been described as being “at the vanguard of the independent publishing movement.” Our reviews feature a unique tripartite ranking system that captures the different aspects of the movie-going experience. We believe in Truth & Movies. Editorial Design View Original Source Here
If there’s one act that might’ve seemed unexpected at this year’s Coachella Valley Music & Arts Festival, it’s Los Mirlos, the iconic Peruvian group whose distinct blend of psychedelic cumbia conjures the mysticism and vibrant energy of the Amazon jungle. Explore Explore See latest videos, charts and news See latest videos, charts and news In their native country, Los Mirlos (named after the blackbirds of the Peruvian jungle) are legends, who have carved out a legacy that transcends generations. Today, founder and lead vocalist, Jorge Rodríguez Grández, plays alongside his two sons, Jorge L. Rodríguez (musical director, pianist and guitar)…
Tom Wiggins / Wired: A look at the tactile devices from OneCourt, Field of Vision, and Touch2See that help visually impaired spectators follow live sports with their fingers — These three companies have developed tactile devices that help visually impaired spectators follow the live action playing out on the field. View Original Source Here
17 Apr 2025 Startup Stories & Market Moves: New Reads to Watch Whether you’re scaling your first venture or just love a good market shake-up, this week’s business and finance novel picks are packed with ambition, strategy, and a touch of suspense. Startup Stories & Market Moves brings you fresh narratives that dive into disruptive ideas, high-stakes deals, and the minds behind the money. These reads don’t just inform—they inspire. Let’s see what’s hitting the shelf this week. The Bond: Succeeding in Sales and Unlocking the Power of Relationship Building by Sandra Rojas Release Date: March 26, 2025 The Bond…
The capsid-protein language model (CAP-PLM) predicts fitness of AAV2 mutants. Credit: Human Gene Therapy (2025). DOI: 10.1089/hum.2024.227 A new study in Human Gene Therapy describes a machine learning (ML) model that can be used as a surrogate for laborious in vitro experiments. This in silico approach aims to increase the fitness of clinical adeno-associated virus (AAV) capsids to make gene therapies more economically viable for patients. Developing AAV capsids with improved yield, or fitness, is a key strategy for reducing manufacturing costs in order to make gene therapies more affordable. Christian Mueller and co-authors from Sanofi describe a state-of-the-art ML…
Critic’s Rating: 4.5 / 5.04.5If you’re not a Cousin Randy fan after Tracker Season 2 Episode 17, you’re missing out because the character has been a brilliant addition to the Tracker family. Bobby’s cousin has mostly been relegated to Bobby-like duties since he was introduced this season, but he’s made an impact with his funny one-liners and generally low-key attitude, which is in major contrast to Colter’s more stoic approach. The two have made a good team thus far, so teaming them up in person was a clever decision. It paid off in delivering one of the funnier episodes of…
Sydney Sweeney has once again fueled breakup rumors with Jonathan Davino after reportedly stepping out without her engagement ring. The Euphoria star, who was engaged to longtime partner Davino, sent the internet into a frenzy—this time by flashing a noticeably bare ring finger. Sydney Sweeney spotted without ring amid split It all began when a video surfaced showing Sweeney singing karaoke. The clip didn’t offer much context about who she was with, but it showed her enjoying a carefree night. Sydney Sweeney’s hand was seemingly missing the ring that once symbolized her engagement to Jonathan Davino. The next day, an…
Over the past few weeks, Sleep Token have steadily been teasing new information regarding Even in Arcadia (their highly anticipated follow-up to 2023’s Take Me Back to Eden). Well, the mysterious group have finally revealed the full track listing for Even in Arcadia, and fans have a lot of jokes and theories.Even in Arcadia’s Full Track ListingLast Friday (April 18), Sleep Token posted to Instagram an image – which you can view below – containing all 10 tracks on Even in Arcadia alongside the comment: “Prepare. Even In Arcadia, May 9th.”As you can see, the rundown of tunes is as follows:01. “Look…
My non-fashion friends just asked me what the best leather sandals of the season were and I had a lot to say about it.There’s always that shoe. The one that quietly dominates every wardrobe for a season, popping up on pavements, in front-row photos, and on all the best dressed people you pass in cafés. Autumn has its loafers, winter gets all snug and booted up—but when spring hits, sandals step in (quite literally) to remind us that style doesn’t have to be heavy-handed. And this year, the best leather sandals are doing more than just filling the seasonal slot—they’re…
Gemini Advanced — the AI service that’s bundled with the Google One AI Premium plan — will be free for a year for college students in the US. Students can now claim 15 months of access to Gemini Advanced, as the company seeks to compete with rival OpenAI’s recent decision to provide two months of ChatGPT Plus for students in the US. As part of the promotion, users will also have access to 2TB of storage for Google products on their personal account, along with other Gemini AI features.Google’s Gemini Advanced Offer is Limited to US StudentsAccording to details on…
Welcome to the Sunday edition of Today in Books, where we recap the stories readers were most interested in this week. New Study Finds That Book Bans Increase Readership of Inclusive Content Researchers at Carnegie Mellon and George Mason University have published a new study about the impact of book bans on the consumption of banned books, and the results might surprise you. Using book circulation data from a “large library content and services supplies to major public and academic libraries in the United States” about the top 25 most-banned titles, found that: Book bans increase the circulation of banned books by 12% compared…
Earth-based lifeforms known as lichens may be tough enough to survive on Mars, a new study suggests.Scientists came to this conclusion after blasting the lichens with a year’s worth of Martian radiation in less than a day during a lab experiment — and the terrestrial lifeforms survived the process.Mars is not an easy place to live. The Red Planet is essentially one giant desert with a minimal atmosphere, low temperatures and no liquid water at its surface. But the biggest barrier to life on Mars is the lack of a strong magnetic field, which protects against the constant bombardment of…
From the moment Troy Bolton and Gabriella Montez took the stage to sing “The Start of Something New” on New Year’s Eve in 2005, we knew we believed in love. Okay, well, maybe our road to loving love stories wasn’t that instantaneous, but here at Swooon, we’ll be the first to admit that whether you grew up watching Zenon: Girl of the 21st Century in 1999 or Descendants in 2015, the Disney Channel Original Movie enjoyer to rom-com aficionado pipeline is the real deal. View Original Source Here
Miller Lite and Pringles may just be the mash-up you didn’t know you needed.Not something you’ve been clamoring for? What if I told you there was meat involved with this crispy snack?What Do Miller Lite Pringles Taste Like?Miller Lite and Pringles announced this week that they had developed a “first-of-its-kind innovation.” The Pringles x Miller Lite collab brings the debut of two limited-edition chip flavors.Pringles x Miller Lite Beer Can Chicken is touted as tasting like roasted chicken with hints of garlic, onion and beer.Beer can chicken pringlesPringles/CanvaPringles x Miller Lite Griller Beer Brat combines black pepper, caramelized onion, and…
Kendrick Lamar and SZA launched their “Grand National Tour” (get tickets here) in Minneapolis, Minnesota on Saturday, teaming up for a massive 52-song, nine-act set that saw the longtime collaborators perform both together and solo as they ran through their respective catalogs. Get Kendrick Lamar and SZA Tickets Here Lamar opened with the live debut of GNX standout “wacced out murals” along with “squabble up,” followed by To Pimp a Butterfly staples like “King Kunta” and “ELEMENT.” From there, SZA took the spotlight with a run of Ctrl favorites including “Love Galore,” “Broken Clocks,” and “The Weekend,” before the two came…
Rocky Kramer will be hosting “Ace of Space” on this week’s episode of Rocky Kramer’s Rock & Roll Tuesdays on Twitch. Tune into Twitch on Tuesday, April 22nd, 2025 at 7 PM PT for this amazing show. Rocky Kramer is a guitar virtuoso, often being compared to the greatest guitar players in the world. Rocky has performed on shows with some of the greatest musicians on the planet including Ozzy Osbourne, John Lodge, Steve Vai, Leland Sklar, Kenny Aronoff, Tommy James, Verdeen White, Ten Years After, BuckCherry, Rick Wakeman and more. Rocky’s first studio album, “Firestorm” is now available worldwide…
I’m a big fan of using the right tool for the job in the kitchen. No surprise there, yet I frequently get that FOMO-y feeling that something new or different might be better than what I own.Several months ago, I looked at a set of carbon steel knives made in Oregon by Steelport. They were beautiful, with their blade patina and sculptural wood handles. I wondered if I was keeping up with the Portlandians, and particularly their bread knives, when I compared it with my inexpensive but high-performing Mercer Culinary Millenia.The Mercer is America’s Test Kitchen’s top pick for serrated…
Accidents Happen and Other Stories by F.H. Batacan ” … ideal for readers who would like some thrilling tales but have limited time.” Soho Crime is a leader in presenting and publishing global mysteries and crime fiction going well beyond the known writers from all parts of Europe and Scandinavia by introducing authors from Central and South America, the Caribbean, Asia, and Africa. There are many exciting authors yet to be discovered. A Trailblazer in Filipino Crime Fiction F.H. Batacan won the Philippine National Book Award in 2002 for her first novel Smaller and Smaller Circles, a detective thriller which…
Real aliens may not be so obvious, if we ever find themNaeblys/Alamy If you’re the kind of person who keeps an eye on astronomical news – or glances at any news site – you may have seen a story about hints of a sign of alien life on an exoplanet called K2-18b. The claim is controversial, but much of the coverage was positive. The problem, I think, is Star Trek, or any other science fiction you might care to mention. Thanks to the budgets that govern television, we’re used to aliens being obvious; they’re usually about 6 feet… View Original…
Characters are the heart of all of our favorite series. You tune in for practically any type of plot as long as the characters are compelling enough and the interesting storylines move you — whether to tears, laughter, or pulling your hair out. The point is that the best part about television viewing is when the characters keep us talking, and that’s why we want to round up some of the standout TV characters of the week. (Robert Voets/CBS) Of course, we’ll never know if you’re into this unless you tell us. So, hit the comments, save our posts, share…
Ryan Coogler: ‘I’m more confident in my film language than I am in my English’ About Little White Lies Little White Lies was established in 2005 as a bi-monthly print magazine committed to championing great movies and the talented people who make them. Combining cutting-edge design, illustration and journalism, we’ve been described as being “at the vanguard of the independent publishing movement.” Our reviews feature a unique tripartite ranking system that captures the different aspects of the movie-going experience. We believe in Truth & Movies. Editorial Design View Original Source Here
The second weekend of the the 2025 Coachella Valley Music and Arts Festival begins today (Friday, April 18), and you’ll be able to watch a lot of the major acts from the comfort of your home via the festival’s stage-by-stage YouTube livestreams. Among the streaming acts are headliners Lady Gaga, Green Day, Travis Scott, and Post Malone, along with marquee names like Missy Elliott, Yeat, Kraftwerk, Arca, and Ravyn Lenae. Plus, Ed Sheeran is playing the second weekend, but Weezer will not. See all the details below.The Best and Worst of Coachella 2025Main Stage Schedule(All times listed in Pacific Daylight…
London’s restaurant scene has always had a certain allure. Whether it’s the old-world glamour of Mayfair’s fine-dining institutions, the cool, experimental charm of East London’s culinary hotspots, or the effortlessly stylish haunts of Soho, dining out in this city is as much about the aesthetic and atmosphere as it is about the food. And in 2025, it’s clear that the capital’s most fashionable restaurants aren’t just serving impeccable dishes—they’re shaping the culture of what it means to dine in style.The most fashionable London restaurants today aren’t necessarily the ones with the most elaborate interiors or even the highest Michelin stars…
Sri Muppidi / The Information: Sales data: AI evaluation startups have modest revenue; Weights & Biases hit $50M ARR by Dec. 2024, but only 2% of that was from its AI evaluation product Weave — Startups whose products evaluate artificial intelligence to make sure it isn’t making things up or delivering unsafe results … View Original Source Here
17 Apr 2025 Twisted Hearts Club: 6 Romance Books for Those Who Loved the Chaos of You If you couldn’t look away from the romantic wreckage of You, or found yourself rooting for love stories that should come with a warning label, we’ve got six brand-new reads that will feed your dark little heart. From psychological tension to toxic devotion, these twisted romances will leave you breathless — and maybe questioning your taste in fictional partners (don’t worry, we’re not judging). Love & Other Cures For the Recently Undead by HJ Ramsay Release Date: February 20 2025 H.J. Ramsay explores…
A mosaic of two pictures showing the rover arm after scanning and sampling one of the rocks discussed in the paper. The rock itself is in the lower right and clearly shows the hole where the sample was collected. The rock was given the informal name “Rochette” by the Perseverance science team. Credit: NASA/JPL-Caltech/ASU In a study co-authored by a Texas A&M University scientist, researchers have revealed new insights into the geological history of Mars’s Jezero Crater, the landing site of NASA’s Perseverance rover. Their findings suggest that the crater’s floor is composed of a diverse array of iron-rich volcanic…
[Warning: The below contains MAJOR spoilers for 9-1-1 Season 8 Episode 15 “Lab Rats.”] Athena (Angela Bassett) has lost another loved one. This time, her husband Captain Bobby Nash (Peter Krause), in a shocking twist at the end of the latest 9-1-1 episode. Early on in the episode, Bobby knew he was going to die, which means he knew throughout all his conversations with Athena over the phone; he realized that his oxygen line was torn in the explosion in the previous episode — so he was exposed to a super strain of CCHF (Crimean–Congo hemorrhagic fever) — and kept quiet while…
Netflix’s new TV and movie releases for April 21-27, 2025, include Bullet Train Explosion, You Season 5, Havoc, Part 2 of Pokémon Horizons: Season 2: The Search for Laqua, and many others. On April 23, the film Bullet Train Explosion drops on Netflix. It focuses on a panic-stricken situation on a Tokyo-bound bullet train, which can explode if its speed goes below 100 kph. The authorities decide to go to great lengths to save everyone’s lives on the train. Further, You Season 5 premieres on the streaming platform. The season focuses on Joe Goldberg returning to New York City to…