MmpL3 is the major target for discovery of new anti-tuberculosis drugs. Zgurskaya and co-authors isolated this target from bacterial cells and reconstituted it in artificial membranes. This creates a powerful tool to characterize and develop new drugs. Credit: Helen Zgurskaya Mycobacterium tuberculosis, the causative agent of tuberculosis, remains the leading cause of infectious disease worldwide, affecting approximately a quarter of the globe’s population. Treatment of infections is problematic due to the emergence of drug-resistant strains; however, University of Oklahoma professor Helen Zgurskaya, an expert in antibiotic resistance, is leading research on new potential therapeutic treatments for the disease. Zgurskaya, a…
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Image Source: Getty Images For Louis Vuitton/Pascal Le Segretain Before gender fluid fashion became more socially acceptable in the US, celebrities like David Bowie, Dennis Rodman, Prince, and Billy Porter were confidently and unapologetically sporting androgynous styles. But outside of Juan Gabriel, we never really had a Latino icon that normalized this within our communities. But artists like Bad Bunny, Maluma, and J Balvin have really been doing their part to change that. In fact, when it comes to fashion, reggaetonero J Balvin has proven he’s not afraid of breaking the gender-restricting rules that are often placed on men —…
Michael Calore: Probably never. Close to never.Lauren Goode: Well, in this case, I think you might actually agree with them because I’ve heard you talking about your Instagram experience lately and it seems like it’s not very good.Michael Calore: Right. It makes me deeply uncomfortable to open Instagram these days.Lauren Goode: Why is that?Michael Calore: Well, I’d love to tell you all about it.Lauren Goode: All right. Let’s talk about it.[Gadget Lab intro theme music plays]Lauren Goode: Hi, everyone. Welcome to Gadget Lab. I’m Lauren Goode. I’m a senior writer at WIRED.Michael Calore: And I’m Michael Calore. I’m a senior…
Carly Rae Jepsen has unveiled her latest single “Beach House” and its accompanying music video. Watch it below. Jepsen revealed the song’s inspiration in a TikTok ahead of its release, saying: “Caught a song idea a while back I’ve been wanting to share. It’s silly. It’s fun. I blame summer and my sister. And dating apps and the experiences so bad that they immediately have to turn funny or how else could we cope? Happy dancing and/or happy nightmares.” “Beach House” serves as the second preview of the singer’s upcoming sixth album, The Loneliest Time, which she announced earlier this…
A brand new trailer for the upcoming animated series, Tekken: Bloodline, has revealed that the series will premiere on Netflix on August 18, 2022.RELATED: Netflix Announces Tekken: Bloodline Alongside Teaser TrailerThe newest trailer shows off more of the series, including the journey that Jin Kazama — who was first introduced in 1997’s Tekken 3 — embarks on with the goal of seeking out his grandfather, the infamous Heihachi Mishima, to train for a major tournament.Check out the new trailer for Tekken: Bloodline below:Tekken: Bloodline marks the latest video game adaptation that Netflix is taking a swing on, having already succeeded in its League of Legends adaptation Arcane,…
26 Jul 2022 Hold on to the edge of your seat as we hunt for clues and solve the case with these exciting new mystery and thriller books for the week! There are so many bestselling authors with new novels for you to dive into this week including Paige Dearth, S. R. Leinbeck, Cyn Mackley & Emma Jameson, and many more. Enjoy your new mystery, thriller, and suspense novels. Happy reading! Related grant scrolls_pure; if (shouldBeFixed && !isFixed) { header.addClass(“sticky”); isFixed = true; } else if (!shouldBeFixed && isFixed) { header.removeClass(“sticky”); isFixed = false; } e.preventDefault(); }); }); }); ]]> Read The…
Jamie Farr hosts “M*A*S*H: The Best by Farr” A Weeklong Presentation of His Favorite Episodes’ to help celebrate the MeTV Network commemorate M*A*S*H’s 50th anniversary. The special weeklong presentation includes Jamie Farr’s favorite episodes, hosted commentary, memories, and stories from his time as co-star of one of television’s greatest all-time favorites. “M*A*S*H: The Best by Farr” airs September 12-16, 2022, from 7-8 pm ET/PT on MeTV, with two of Farr’s hand-picked “best of” episodes airing nightly. M*A*S*H is part of MeTV’s memorable and entertaining weeknight lineup, airing two back-to-back episodes starting at 7 pm ET/PT every Monday-Friday and Sunday night.…
Statistics showing 67% of early career researchers want to publish open access but 70% lack the funds to do so from a new global study from IOP Publishing, AIP Publishing, the American Society of Physics and Optica Publishing Group (formally OSA). Credit: n/a A new global study from AIP Publishing, the American Physical Society (APS), IOP Publishing (IOPP) and Optica Publishing Group (formerly OSA) indicates that the majority of early career researchers (ECRs) want to publish open access (OA) but they need grants from funding agencies to do so. Over 3,000 physical science researchers from across the globe participated in…
Getty Images I won’t lie to you: I’ve taken numerous trips to salon for in-office hair removal, from sugaring to waxing, but I always return to my first true love, depilatory creams. Depilatory creams, aka hair removal creams, come in a lotion-like consistency that you can glide on your legs, armpits, and in some cases, your face, to remove unwanted hair. It breaks down the hair cuticle to completely remove it from the surface quickly. Best of all? It’s painless. Oh, and the options are endless. Want to remove hair without disrupting your shower time? What about that embarrassing patch…
Taron Egerton has reportedly met Marvel Studios President Kevin Feige about playing Wolverine in a future project. The 32-year-old actor told a publication that he would love to essay the iconic X-Men character in the Marvel Cinematic Universe if things work out. That said, Egerton is a bit “apprehensive” about the same, as most people still associate the human mutant with Hugh Jackman. Egerton, however, didn’t comment on what was discussed in his said meeting with Feige, which suggests that nothing is set in stone at the moment.Egerton told The New York Times: “I don’t think it would be wrong…
[] { e.preventDefault(); }); ]]> Skip to main content The Chicks have turned their new tour into a family affair with their kids getting in on the fun! The Daily A daily briefing on what matters in the music industry ad {{ result.published_at | date: “%h %d, %Y” }} {{ result.name }} ]]> 0) { __qc.qpixelsent.length = 0; } // First Quantcast Tag _qoptions={ qacct:”” }; quantserve(); } catch(err) {} // Track Comscore unless it’s a gallery and has been tracked if ( window.pmc.comscoreTracked && -1 === window.pmc.comscoreTracked.indexOf( document.location.href ) ) { try { setTimeout(function(){var url = “http” + (/^https:/.test(document.location.href)…
Hit the Road review – Sardonic humour meets engrossing tragedy 3 && args[2] === 2 && typeof args[3] === ‘boolean’ ) { gdprApplies = args[3]; if (typeof args[2] === ‘function’) { args[2](‘set’, true); } } } else if (args[0] === ‘ping’) { var retr = { gdprApplies: gdprApplies, cmpLoaded: false, cmpStatus: ‘stub’ }; if (typeof args[2] === ‘function’) { args[2](retr); } } else { if(args[0] === ‘init’ && typeof args[3] === ‘object’) { args[3] = { …args[3], tag_version: ‘V2’ }; } queue.push(args); } } function postMessageEventHandler(event) { var msgIsString = typeof event.data === ‘string’; var json = {}; try {…
After sustaining nerve injuries, mice wake up more often during non-REM sleep – a sign that sleep disruption could help identify nerve pain and the best treatments for it Health 18 May 2022 By Grace Wade Nerve pain can cause sleep disturbancesShutterstock / SB Arts Media Pain from nerve injury causes distinct changes in mice’s sleep patterns that aren’t seen with other types of pain. The finding suggests that sleep disturbances could be used to measure and diagnose such neuropathic pain. Quantifying pain is notoriously difficult. Most methods are subjective, such as asking patients to rate their discomfort on a…
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The Criminal Minds revival is a go, but don’t expect things to go smoothly when our favorite members of the BAU unite to solve crimes. TV Line dropped some insider knowledge about the 10-part new season, and we’re a bit worried about Prentiss (Paget Brewster). “I am hearing that in the Paramount+ revival, Prentiss’ role as team leader will be challenged by a new deputy director who doesn’t quite share her view on how best to run the BAU,” the outlet shared in response to a fan’s question. It wouldn’t be Criminal Minds without some drama, and we’re sure fans…
As monkeypox cases continue to rise in the U.S. and the rest of the world, many of those most affected by the virus say they cannot access an effective treatment. The current monkeypox outbreak has caused more than 21,100 confirmed cases worldwide, including more than 4,900 in the U.S. The virus has infected people in Central and West Africa for decades but recently started circulating abroad, so far primarily among men who have sex with men. It spreads through close skin-to-skin contact, including during sex. The virus causes painful, blisterlike lesions—in the current outbreak, these are often found on the…
We all experience days when we just don’t have the time or the mental capacity to think about our outfits. Don’t worry—it happens to the best of us. This is where the throw-on dress comes in. Now, what sets a dress apart from a throw-on dress? It’s quite simple. Where some dresses might feel tight and restricting, throw-on dresses are the opposite. Often loose or stretchy, they’re comfortable to wear and don’t require too much effort, particularly when selecting which underwear to wear underneath them. (I like to look for a dress that I don’t have to wear with a…
[Thread] A look at Helium, a crypto network of 500K+ IoT hotspots, which raised $365M from a16z and others and generates an est. $6.5K/month in network revenue — .@Helium, often cited as one of the best examples of a Web3 use case, has received $365M of investment led by @a16z. Regular folks have also been convinced to spend $250M buying hotspot nodes, in hopes of earning passive income. The result? Helium’s total revenue is $6.5k/month https://twitter.com/… Read The Full Article Here
With so many new metal and hard rock albums being released each week, it can be difficult to keep up. We’re making things a lot easier for you by keeping track of all the 2022 releases in one convenient location.Check back often or bookmark this page, because this list is updated on a regular basis. Dates are supplied by record labels and are subject to change.LOUDWIRE PLAYLISTS:August 5, 2022Amon Amarth – The Great Heathen Army (Metal Blade)Andy McCoy – Jukebox Junkie (Cleopatra)Einherjer – Norse And Dangerous (Live… From The Land Of Legends) (Napalm)H.E.A.T. – Force Majeure (earMusic)In Hearts Wake -…
The wooden boy comes to life again in the first trailer for Guillermo del Toro’s Pinocchio 3 && args[2] === 2 && typeof args[3] === ‘boolean’ ) { gdprApplies = args[3]; if (typeof args[2] === ‘function’) { args[2](‘set’, true); } } } else if (args[0] === ‘ping’) { var retr = { gdprApplies: gdprApplies, cmpLoaded: false, cmpStatus: ‘stub’ }; if (typeof args[2] === ‘function’) { args[2](retr); } } else { if(args[0] === ‘init’ && typeof args[3] === ‘object’) { args[3] = { …args[3], tag_version: ‘V2’ }; } queue.push(args); } } function postMessageEventHandler(event) { var msgIsString = typeof event.data === ‘string’;…
This content contains affiliate links. When you buy through these links, we may earn an affiliate commission. You know how a lot of authors have the book they’re known for? For example, Toni Morrison is most well-known for Beloved and Amy Tan for The Joy Luck Club. But these authors, like so many others, also have under-the-radar books few have heard of and even fewer have read. This quiz is designed to match you up with just such a book. There’s nothing quite as fun as embarking on a literary adventure into the unknown. But when you’re reading a book…
Partner Track, starring Teen Wolf’s Arden Cho, finally has a premiere date. Netflix on Friday confirmed the series will premiere all episodes of its first season on August 26. “Ingrid Yun (Arden Cho), a 1st generation Korean American and the first lawyer in her family, experiences the trials and tribulations of excelling at the prestigious (but old school) law firm, Parsons Valentine,” the logline teases. “With the support of her friends, she battles through workplace challenges to break through the glass ceiling on her path to become partner,” it continues. “But will her drive and ambition leave room for love?”…
A stunning new image from the James Webb Space Telescope captures the gorgeous Cartwheel Galaxy in never-before-seen detail. The telescope’s composite image, released Tuesday (Aug. 2) furthers our understanding of the peculiar wheel-like star system.The Cartwheel Galaxy is a chaotic galaxy shrouded in hot dust, 500 million light-years from Earth. And it hides a violent past.”Its appearance, much like that of the wheel of a wagon, is the result of an intense event — a high-speed collision between a large spiral galaxy and a smaller galaxy not visible in this image,” NASA representatives said in a statement. While the Cartwheel Galaxy…
Photography by pHarrisDesigns It’s been a big week in beauty. By Natasha Boateng Date July 30, 2022 Shea Moisture celebrates Toronto’s Caribbean Carnival with a pop-up Photography by pHarrisDesigns The Toronto Caribbean Carnival is back in full force this weekend after two years of pandemic-related cancellations, and Shea Moisture, a popular haircare brand among those with curly and coily hair, is joining in on the important cultural celebration with a four day pop-up (the brand’s second Toronto Caribbean Carnival-themed event to date). Taking over the city’s downtown Stackt Market until Monday, August 1st, the Shea Carnival experience features complimentary hairstyling…
[Thread] A look at Helium, a crypto network of 500K+ IoT hotspots, which raised $365M from a16z and others and generates an est. $6.5K/month in network revenue — .@Helium, often cited as one of the best examples of a Web3 use case, has received $365M of investment led by @a16z. Regular folks have also been convinced to spend $250M buying hotspot nodes, in hopes of earning passive income. The result? Helium’s total revenue is $6.5k/month https://twitter.com/… Read The Full Article Here
Radiohead guitarist Ed O’Brien says that “there’s no Radiohead at the moment.” In his recent interview with Shaun Keaveny from The Line-Up Podcast, the guitarist revealed that the future of the band is currently up in the air.When O’Brien was asked if the band would eventually get back together his response was, “It might happen, but the other thing is…it might not. And does that matter?” The guitarist says Radiohead are “not going to be one of those bands that gets together for the big payday.””The thing with Radiohead, we could do something in a couple of years. We might…
The Rock has always looked like a superhero. Now he finally gets to play one.He’s the title role in Warner Bros.’ Black Adam, based on the long-running character from DC Comics. The character was introduced as a villain in Captain Marvel comics (now he’s called Shazam, because comics are never simple and easy to understand) but in recent years Black Adam has become more of a complex antihero, and that’s the version we see in the film. He’s a guy who is out for “justice” but his methods and idea might be a little more… brutal than your typical superhero.See for yourself in the…
Researchers compared the rate of long covid among people who were vaccinated after catching covid-19 with those who developed long covid before being vaccinated Health 18 May 2022 By Jason Arunn Murugesu A person receiving a covid-19 vaccine in Glasgow, UK, in July 2021ANDY BUCHANAN/AFP via Getty Images Getting vaccinated against covid-19 after being infected with the coronavirus may lower your risk of long covid. Daniel Ayoubkhani at the Office for National Statistics (ONS) and his colleagues looked at more than 28,000 people living in the UK, aged 18 to 69. All the participants tested positive for the SARS-CoV-2 virus…
This content contains affiliate links. When you buy through these links, we may earn an affiliate commission. As a dog owner and all around animal lover, I’ve always wondered what my dog or the animals around us had to say. Would they have some great insights to impart on the world? Maybe something like slow down and enjoy the world? Or would it just be a litany of feed me, feed me, feed me? The field of animal consciousness has been exploding as previous paradigms of what it means to be human are being dissolved and we discover that diverse…
An “All Winners” season had a lot of expectations to live up to during RuPaul’s Drag Race All Stars Season 7. These weren’t queens returning for their redemption and a spot in the Drag Race Hall of Fame. These were all winners, honey! Everyone had a crown and won their season, so we knew they could bring it and win the whole thing. But if the queens were competing against the best, did they bring their best? That’s the big question the competition had to answer. Now that all has been said and done, RuPaul’s Drag Race All Stars Season…